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Recent research has discovered that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a particular mutation which makes them more likely to benefit from naltrexone, compared with about 20% of Caucasians and much less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director of the UCLA Addictions Laboratory. The findings are available online ( inside the journal Neuropsychopharmacology and will be published in an upcoming print edition with the journal. Using two separate drugs to lose weight naturally can be very effective you can find combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the people who go through it one should err on the side of caution and let the FDA do its job and demand some research be done so that the public knows the side effects and risks of the medications before we bring them. Keep in mind that drug companies come in business to generate money and that they would say almost anything to keep people on their medications. Researchers discovered that participants taking this drug for a year, dropped a few pounds within a month and have kept the load off through the 56 weeks in the study. Contrave is really a combination of the drugs naltrexone and bupropion, which usually reflect a brand new trend of weight-loss drugs which might be made up of more than one active ingredient, that might make them more effective and safer. Combo-pilling is the newest fad or even better the newest to come under scrutiny and thus it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular will be the fact that since right now there aren't long term prescription diet pills that have been authorized by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be authorized by the FDA. Seizures certainly are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug may also raise blood pressure and heartbeat, and really should not be used in individuals with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure level and pulse rate and must stop used in patients with uncontrolled high blood pressure level, along with by a person with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients with a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients to the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation. Acamprosate also actively works to eliminate the desire to drink through the elimination of the the cravings for alcohol consumption. The major difference between Naltrexone and Acamprosate is Acamprosate just isn't yet available in the United States. While it has become widely studied in Europe the precise chemical believe that it works remains to be unknown. It is believed that it disrupts receptors within the brain which process glutamate, which in place alters the best way ones body reacts to alcohol intake. Several of the European studies show a lot of promise with Acamprosate in that some of the patients had a virtually double success rate for staying sober.

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